(Reuters) -The U.S. Food and Drug Administration is probing the death of a patient who developed harmful antibodies after taking Takeda Pharmaceuticals' blood disorder therapy, the health regulator said on Friday.
The pediatric patient died about 10 months after starting Takeda's drug Adzynma as a preventive therapy, the agency said.
The child had congenital thrombotic thrombocytopenic purpura (cTTP), an inherited condition that causes blood clots in small vessels and can lead to organ damage.
The FDA said the child developed antibodies that blocked the activity of ADAMTS13, an enzyme critical for blood clotting.
Takeda did not immediately respond to Reuters request for comment.
Adzynma, approved in 2023 as the first therapy for cTTP, replaces the ADAMTS13 protein to help prevent dangerous blood clots.
The agency added it has received multiple postmarketing reports of patients developing neutralizing antibodies to ADAMTS13 after treatment with Adzynma.
(Reporting by Kamal Choudhury in Bengaluru; Editing by Vijay Kishore)
latest_posts
- 1
Decrease in Home Buy Credits and Home loan Renegotiating Rates: An Outline of Latest things - 2UAE-backed Yemeni Southern Transitional Council denies disbandment rumors
- 3The most effective method to Succeed in Your Profession with a Web based Advertising Degree
- 4Brazil's Bolsonaro to continue his sentence at home because of poor health
- 5The most effective method to Execute a Lung-Solid Eating routine After a Cellular breakdown in the lungs Finding
- Gaza humanitarian efforts reach key milestone as UNICEF vaccinates some 13,000 children
- Step by step instructions to Pick the Right Web-based Degree Program
- Only 30% of young people in Israel optimistic about future, Aluma survey reveals
- Heading to Florida for NASA's Artemis 2 moon launch? Here's what to know before you go
- Manual for Famous people Known for Their Altruistic Endeavors
- Last supermoon of the year, the cold moon, seen across the U.S.: See the photos
- Remains of banker missing since 1999 found on California beach by family looking for seashells
- Scientists are getting our robotic explorers ready to help send humans to Mars
- Pick Your Favored kind of sandwich
